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Initially after being diagnosed, she exhibits sensation seeking: staying out all night, using recreational drugs and having repeated one-night stands with women.

She later ceases to behave self-destructively after a near-death experience in the episode "Last Resort", wherein she realizes her conviction to live, agreeing to participate in a Huntington's disease drug trial and becoming more active in her attempts to prolong her life.

Foreman was the first character to judge her as such; House arrives at the same conclusion at the end of the episode.

She has since made various jokes about dating girls while refusing to confirm or deny her sexuality.

Gregory House after the disbanding of his previous team in the third season finale.

Thirteen has a 50/50 chance of having inherited Huntington's disease from her mother, but she initially refuses to be tested for it as not knowing allows her to live with hope.Although fairly ambiguous in the show, Olivia Wilde has confirmed that Thirteen is indeed bisexual in a July 2008 interview.Hadley's compassion and care for others is one of her best traits, but she has major problems dealing with death and patients that are terminal, perhaps out of fear of her own mortality from her Huntington's disease.It is revealed in the season-four finale that she has the mutation for Huntington's.In "Lucky Thirteen", Thirteen says that her Huntington's is more aggressive, greatly decreasing her life expectancy and hastening the onset of symptoms.

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